We present a debubbler for the removal of air bubbles in aqueous liquids in microfluidics. The
debubbler is realized through an array of cylinder-shaped air-liquid interfaces, or air-pillars, formed
directly into the microfluidic channels by surface tension. The debubbler demonstrated effective
trapping and removal of both chemically generated bubbles several nanoliters to several microliters
in volume and air slugs with several microliters in volume, which were formed by high infusion
rates of bubble series introduced into the microchannel.